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BPS Pharmacotherapy (Part1 and Part2) Sample Questions:

1. Investigators studying the relative nephrotoxicity of two aminoglycosides selected their sample size to detect a reduction in toxicity of 10%. Which of the following is the power of this study if the probability of falsely rejecting the null hypothesis is 0.05 and the probability of falsely accepting the null hypothesis is 0.20?

A) 0.10
B) 0.95
C) 0.05
D) 0.80

2. A 65-year-old man with heart failure is currently receiving digoxin, lisinopril, furosemide, and carvedilol. He is in normal sinus rhythm and is hemodynamically stable. His left ventricular ejection fraction is 30%. Which of the following statements best describes the role of digoxin therapy in this patient?

A) It can be safely discontinued.
B) It can be synergistic with carvedilol.
C) It can decrease the risk of hospitalization.
D) It can improve mortality.

3. Which of the following pharmacoeconomic analyses incorporates patient preferences regarding health?

A) Cost-utility
B) Cost-effectiveness
C) Cost-benefit
D) Cost-minimization

4. A pharmacotherapy specialist is contemplating Writing a case report on a suspected penicillin induced neutropenia in a patient who received intravenous penicillin G for treatment of infective endocarditis. The specialist has established a temporal relationship between the period of medication administration and the onset of neutropenia, and has excluded other potential causes of the adverse effect.
Which of the following is the most appropriate next step in composing the case report?

A) Describe the incidence, severity, and outcome of penicillin-induced neutropenia for the introduction section of the report.
B) Collect all pertinent patient information, including past medical history, laboratory data, medication history, and consent.
C) Perform a comprehensive literature search to identify existing literature describing neutropenia in penicillin-treated patients.
D) Generate ideas and wording for the patient case summary portion of the report.

5. An investigator decides to perform a correlation analysis of the relationship between the number of cigarettes smoked per day and age. Results show a positive correlation between the two, with an r value of 0.50 and ap value for the correlation equal to 0.03. What is the most reasonable interpretation of this correlation?

A) There is a statistically significant numerical association between age and amount of smoking.
B) Increased age causes students to Smoke more.
C) There is no relationship between age and amount of smoking.
D) Increased age does not cause students to smoke more.

Solutions: